FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Xiao Zhenyu
 2. Date of Event Requiring Statement (Month/Day/Year)
12/06/2018		 3. Issuer Name and Ticker or Trading Symbol
DiaMedica Therapeutics Inc. [DMAC]
(Last)
(First)
(Middle)
2 CARLSON PARKWAY, SUITE 260		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

MINNEAPOLIS, MN 55447		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Voting Common Shares, no par value per share 1,000,000
I
See Footnote (1)
Voting Common Shares, no par value per share 3,850 (2)
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy)   (3) 06/19/2027 Voting Common Shares 5,000 $ 4.82 (4) D  
Stock Option (right to buy)   (5) 04/17/2028 Voting Common Shares 3,000 $ 8.43 (4) D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Xiao Zhenyu
2 CARLSON PARKWAY
SUITE 260
MINNEAPOLIS, MN 55447		   X   X    
Hermeda Industrial Co., Ltd
1289 YISHAN ROAD
ROOM 308, BUILDING A
SHANGHAI, F4 200233		     X    

Signatures

/s/ Amy Culbert, attorney-in-fact 12/06/2018
**Signature of Reporting Person Date
Hermeda Industrial Co., Limited, By: /s/Zhenyu Xiao, Director 12/06/2018
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) These voting common shares are held by Hermeda Industrial Co., Limited, Zhenyu Xiao, Ph.D. is the Director of Hermeda Industrial Co., Limited and has sole voting and dispositive power over the voting common shares held by Hermeda Industrial Co., Limited.
(2) These voting common shares are issuable upon settlement of deferred share units granted under the DiaMedica Therapeutics Inc. Deferred Share Unit Plan.
(3) This stock option vests in 12 equal quarterly installments over three years starting on September 19, 2017.
(4) Represents the conversion of the exercise price from CAD$ to US$ on November 30, 2018.
(5) This stock option vests in 12 equal quarterly installments over three years starting on July 17, 2018.

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